Every Biomarker We Measure to Read How You Age.

Baseline circulating cholesterol; context for every other lipid marker.

The classic 'bad' cholesterol that deposits into artery walls.

Cholesterol being carried away from arteries; higher is generally protective.

All atherogenic cholesterol combined; often a better risk read than LDL alone.

Blood fat that rises with sugar and insulin problems; a metabolic-aging signal.

Triglyceride-rich particles that feed plaque formation.

Signals active clot formation and breakdown; a thrombotic-tone marker.

A quick ratio summarizing overall cardiovascular risk balance.

A strong surrogate for insulin resistance and small dense LDL.

The main protein in HDL; reflects how much protective particle you carry.

Counts every plaque-causing particle; the single best lipid risk marker.

Balance of harmful to protective particles in one number.

Actual count of LDL particles; two people with same LDL-C can differ sharply.

The smallest, most artery-penetrating LDL subtype.

Whether your LDL is large-fluffy (safer) or small-dense (riskier).

Count of protective particles, beyond just HDL cholesterol mass.

Which HDL sizes you carry; large HDL is the most protective.

A largely genetic, independent driver of heart and stroke risk most doctors never check.

Blocks nitric oxide, stiffening vessels; an early sign the endothelium is aging.

Reflects combined kidney and cardiovascular strain before standard markers move.

Directly measures LDL that has become inflammatory and plaque-active.

An enzyme signaling inflammation inside the artery wall specifically.

Marks white-cell activity attacking the vessel lining; flags unstable plaque.

Impairs clot breakdown; links clotting risk to endothelial and metabolic aging.

An amino acid that damages vessels and neurons when methylation falters.

The workhorse marker of low-grade, aging-accelerating inflammation.

A clotting protein that also tracks inflammation and vascular risk.

Signals fibrosis and stiffening of the heart muscle.

Released when the heart is under mechanical stress or strain.

Lipid molecules that predict plaque instability and cardiac events.

Tiny protein leak into urine; one of the earliest signs of vessel-lining damage.

A more sensitive kidney-filtration marker that also tracks cardiovascular risk.

Baseline blood sugar; chronically high accelerates aging across every tissue.

Your average blood sugar over ~3 months, showing glycation load.

A 2–3 week blood-sugar average, useful when A1c is unreliable.

An insulin-sensitivity calculation complementary to HOMA-IR.

A protective fat-cell hormone; higher levels track healthier metabolism and longevity.

Baseline circulating cholesterol; context for every other lipid marker.

Baseline circulating cholesterol; context for every other lipid marker.

Reflects glutathione-building capacity central to mitochondrial aging.

Calories burned at rest, measured by breath analysis; reveals metabolic efficiency.

Signals beta-cell strain — one of the earliest metabolic-aging markers.

An NMR marker of composite chronic inflammatory burden.

Often rises years before glucose; an early window into metabolic aging.

Measures how hard your pancreas is working to make insulin.

Combines glucose and insulin into a single insulin-resistance score.

The satiety hormone; resistance signals metabolic dysfunction and fat gain.

Links body fat to insulin resistance and inflammation.

Shows whether cells are burning fat for clean energy.

An entry fuel to the mitochondria; pairs with lactate to read energy flow.

Peak oxygen use during exercise; one of the strongest predictors of lifespan.

Which fuel your body prefers at rest and under load.

Rules out latent autoimmune diabetes in adults.

The pituitary's signal to the thyroid; the standard first-line screen.

The storage thyroid hormone available to your tissues.

The active hormone that actually drives cellular metabolism.

Total circulating active hormone, bound and free.

Total circulating storage hormone.

A 'brake' hormone that rises under stress and blocks metabolism.

Drives overactive autoimmune (Graves') thyroid.

Helps interpret thyroid binding and free hormone levels.

Reflects growth-hormone activity; a key, double-edged longevity lever.

The carrier protein for thyroid hormone; alters how much is free and active.

A stable stress-and-vasopressin marker reflecting chronic HPA load.

Flags autoimmune adrenal failure (Addison's).

The main marker of autoimmune (Hashimoto's) thyroid attack.

A second autoimmune thyroid antibody.

Overall level of the primary anabolic hormone in both sexes.

Free plus loosely-bound testosterone your body can actually use.

The main estrogen; critical for bone, brain, and vessel aging in both sexes.

The gentlest estrogen, relevant to tissue and reproductive health.

An adrenal 'youth' hormone that declines steadily with age.

Evening cortisol; should fall for restorative sleep.

The master precursor from which many steroid hormones are made.

A pituitary hormone tracking reproductive and ovarian aging.

Elevated levels can suppress sex hormones and signal pituitary issues.

The brain's signal driving cortisol output.

Kicks off the blood-pressure hormone cascade; paired with aldosterone.

Your master sleep-and-repair hormone across the night.

The unbound, biologically active fraction that reaches tissues.

Controls how much sex hormone is free and active.

A secondary estrogen that becomes dominant after menopause.

Balances estrogen and supports sleep, mood, and nervous system calm.

Morning stress hormone; should be high to start the day.

Four daily samples mapping your full stress rhythm, not one snapshot.

An adrenal pathway marker for hormone production.

Partners with FSH to regulate sex hormone production.

A potent testosterone derivative affecting hair, skin, and prostate.

Regulates blood pressure through salt and fluid balance.

How you break down estrogen; certain paths carry more long-term risk.

The broad first-line screen for systemic autoimmune activity.

A specific marker for lupus and its activity.

Overlaps lupus and mixed connective-tissue disease.

Partners with SS-A in Sjögren's diagnosis.

Points to a limited form of scleroderma.

Associated with drug-induced lupus.

Central to mixed connective-tissue disease.

Overlap myositis and scleroderma marker.

Myositis antibody with cancer and calcinosis associations.

Antisynthetase marker often with prominent lung involvement.

Dermatomyositis-associated autoantibody.

Amplifies lung-disease risk across many autoimmune conditions.

Classic dermatomyositis antibody with skin findings.

The traditional rheumatoid arthritis antibody.

Detects vasculitis — inflammation of the blood vessels themselves.

Points to primary biliary autoimmune liver disease.

Specific autoimmune hepatitis antibody.

A bundle screening for blood-vessel-directed autoimmune inflammation.

Marks autoimmune gastritis that impairs B12 absorption.

Neural autoantibodies behind autoimmune cognitive decline.

Strength and staining pattern that point toward specific conditions.

Highly specific autoantibody for lupus.

Linked to Sjögren's, lupus, and dryness syndromes.

Marks systemic sclerosis with organ involvement.

The classic myositis/lung-involvement antibody.

Supports lupus diagnosis and activity.

Antisynthetase antibody linked to interstitial lung disease.

Flags rapidly progressive lung disease in dermatomyositis.

Rare antisynthetase antibody tied to lung and muscle disease.

Antisynthetase antibody linked to myositis and ILD.

Marks a severe necrotizing myopathy.

Myositis antibody strongly associated with underlying cancer.

Polymyositis-scleroderma overlap marker.

A more specific, earlier marker of rheumatoid arthritis.

Marker for autoimmune liver disease.

Autoimmune hepatitis marker.

The defining antibody of Goodpasture's — autoimmune attack on kidney and lung.

Maps muscle-directed autoimmunity behind weakness and lung disease.

Confirms pernicious anemia, an autoimmune cause of B12 loss.

A waste product reflecting kidney filtration and protein turnover.

Helps distinguish kidney issues from hydration and other causes.

High levels drive gout and link to metabolic and vascular aging.

A simple read of hydration and kidney concentrating ability.

A liver and muscle enzyme released with tissue stress.

Reflects liver, bile-duct, and bone activity.

A breakdown product of red cells; also a mild antioxidant.

The main blood protein; low levels track frailty and aging.

Balance of the two protein classes; shifts with inflammation.

Helps confirm whether elevated ALP is liver-related.

Reflects cell turnover, kidney filtration, and immune activation.

Muscle byproduct used to estimate kidney filtration.

The headline number for overall kidney function.

Detects early protein leakage signaling kidney and vessel stress.

Precise measure of how well kidneys concentrate urine.

The most liver-specific enzyme; rises with fatty liver.

Sensitive to bile flow, alcohol, and oxidative stress.

Overall protein in blood, from nutrition and liver output.

Immune and transport proteins; part of the protein picture.

A general marker of cell turnover and tissue damage.

A safety-gate enzyme; deficiency risks red-cell breakdown with oxidative therapy.

Marks a severe necrotizing myoaA short-half-life protein giving a real-time read of nutrition status.pathy.

How many oxygen-carrying cells you have.

The proportion of blood made of red cells.

Average hemoglobin per red cell.

Variation in red-cell size; higher values track aging and mortality risk.

Platelet size, reflecting production and clotting tendency.

First-responder immune cells for bacterial threats.

Cleanup and antigen-presenting immune cells.

Involved in allergic and inflammatory responses.

The oxygen-carrying protein inside red cells.

Average red-cell size; clues to B12, iron, and folate status.

Hemoglobin concentration within red cells.

Cells that form clots; part of bleeding and inflammation balance.

Your total immune-cell army.

The immune cells behind memory and viral defense.

Rise with allergies and parasites.

A simple, powerful index of systemic inflammatory aging.

Circulating iron available for oxygen transport and energy.

How much iron your blood can carry.

A hormone-like vitamin central to immunity, bone, and healthy aging.

Essential for nerves, energy, and red-cell production.

Key for methylation, DNA repair, and homocysteine control.

A fat-soluble antioxidant protecting cell membranes.

A mitochondrial spark plug that declines with age and statins.

A plant-derived vitamin A precursor and antioxidant status marker.

Your iron storage tank; also rises with inflammation.

The percentage of iron-carrying capacity currently filled.

The active form, useful for interpreting complex cases.

The truly usable fraction of B12, more sensitive than total.

Supports vision, skin, and immune-barrier integrity.

Antioxidant and essential cofactor for collagen synthesis.

Reveals true tissue-level B12 deficiency.

Core electrolyte for fluid balance and nerve signaling.

Works with sodium in fluid and acid-base balance.

A calculated check on hidden acid-base disturbances.

Cofactor for 300+ enzymes; commonly depleted.

Partners with calcium in bone and cellular energy.

Drives immunity, wound healing, and hormone production.

Antioxidant mineral essential for thyroid and glutathione.

A cumulative neurotoxin stored in bone for decades.

Environmental toxin linked to cancer and vascular disease.

Critical for heart rhythm and muscle function.

Reflects acid-base status of the blood.

Vital for bone, nerves, and muscle contraction.

A truer measure of magnesium inside cells.

Needed for connective tissue and iron handling.

An imbalance signals inflammation and oxidative stress.

The main copper-carrying protein and antioxidant.

A neurotoxic metal from fish and dental sources.

Toxins from mold exposure that impair immunity and cognition.

Mold toxins with liver and cancer implications.

Potent mold toxins affecting multiple systems.

The world's most common herbicide, tracked as a body burden.

Plasticizers that disrupt hormones.

A plastics chemical that mimics estrogen.

Solvent-exposure markers affecting the nervous system.

A contaminant that interferes with thyroid function.

Retained contrast-dye metal from MRI scans.

A common mold toxin affecting kidneys and the nervous system.

An immune-suppressing toxin from Aspergillus mold.

A mold toxin with estrogen-mimicking effects.

Pesticide metabolites affecting the nervous system.

Preservatives with endocrine-disrupting potential.

Markers of exposure to a known carcinogen.

A cooking- and smoke-derived toxin.

A broad urine screen of toxic and essential elements.

A neurotoxic metal with widespread environmental exposure.

The direct marker of 'leaky gut' — a loosened intestinal barrier.

Your gut's frontline antibody defense.

Measures digestive-enzyme output from the pancreas.

Gut-bacteria fuels that protect the colon and metabolism

A broad balance signature of the gut ecosystem.

The beneficial species that keep the gut in balance.

Screens for disease-causing gut organisms.

Screens for parasitic organisms disrupting the gut.

Marks neutrophil-driven intestinal inflammation.

Maps delayed immune reactivity to common foods.

A multi-marker read of intestinal permeability beyond zonulin alone.

Broad delayed-reactivity mapping across 90-200+ foods.

Flags active intestinal inflammation.

High activity impairs estrogen and toxin clearance.

Reveals fat malabsorption.

A key resilience metric; diversity falls with aging.

A beneficial microbe tied to a healthy gut lining and longevity.

Overgrowth species that drive inflammation and symptoms.

Detects yeast imbalance affecting gut and immune health.

A stomach bacterium linked to ulcers and B12 loss.

Screens for hidden GI bleeding and barrier damage.

Detects immune response to yeast overgrowth.

Detects bacterial toxin leakage across a compromised gut wall.

The primary blood screen for celiac disease.

A specific antibody to processed gluten fragments.

A highly specific confirmatory celiac test.

Associated with Crohn's-type inflammatory bowel disease.

Associated with ulcerative-colitis-type IBD.

Celiac screen for those with IgA deficiency.

Complements DGP IgA for celiac detection.

Ensures celiac IgA tests are interpretable.

A cluster of antibodies mapping inflammatory bowel disease.

An innate immune alarm elevated in mold and biotoxin illness.

Drives tissue fibrosis and immune dysregulation.

An enzyme that breaks down tissue and opens barriers under inflammation.

A master regulator low in mold-illness patients.

The enzyme that clears dietary histamine; low levels cause intolerance.

Reflects long-term antibody immunity and reserve.

The first-response antibody to new infections.

Frontline defense against viruses and cancerous cells.

A master inflammatory cytokine driving tissue breakdown.

Tests whether immune cells can actually kill pathogens.

Screens for abnormal monoclonal immune proteins.

Measures allergic sensitization to environmental molds.

A complement fragment marking acute innate activation.

Governs new vessel growth; abnormal in chronic inflammatory illness.

A regulatory hormone often depleted in chronic biotoxin illness.

Elevated in mast-cell and allergic-type reactivity.

The master allergy antibody.

Guards mucosal surfaces like gut and airways.

A key immune-balance and immune-aging index.

A central inflammaging cytokine predicting frailty and mortality.

Counts immune-cell populations to reveal immunosenescence.

Elevated in granulomatous conditions like sarcoidosis.

A sensitive check for plasma-cell and paraprotein disorders.

Measures prior immune response and sensitization to specific molds.

The body's master antioxidant, central to detox and longevity.

The core readout of your cellular redox balance.

Measures oxidative damage to cell membranes.

A frontline antioxidant enzyme.

Breaks down hydrogen peroxide inside cells.

A widely used marker of lipid peroxidation and membrane oxidative damage.

Oxidized-protein markers tied to inflammation and aging.

The spent form; its ratio to GSH reveals oxidative load.

A direct marker of oxidative damage to your DNA.

The gold-standard marker of ongoing oxidative stress.

Uses selenium to neutralize peroxides.

A summary score of your overall antioxidant reserve.

Directly measures oxidative damage to the body's proteins.

The body's master antioxidant, central to detox and longevity.

The core readout of your cellular redox balance.

Measures oxidative damage to cell membranes.

A frontline antioxidant enzyme.

Breaks down hydrogen peroxide inside cells.

A widely used marker of lipid peroxidation and membrane oxidative damage.

Oxidized-protein markers tied to inflammation and aging.

Oxidized-protein markers tied to inflammation and aging.

Oxidized-protein markers tied to inflammation and aging.

The spent form; its ratio to GSH reveals oxidative load.

A direct marker of oxidative damage to your DNA.

The gold-standard marker of ongoing oxidative stress.

Uses selenium to neutralize peroxides.

A summary score of your overall antioxidant reserve.

Directly measures oxidative damage to the body's proteins.

Directly measures oxidative damage to the body's proteins.

Directly measures oxidative damage to the body's proteins.

Krebs-cycle intermediates showing mitochondrial energy flow.

Downstream Krebs markers pinpointing where energy production stalls.

Shows fat-burning and ketone production.

A tryptophan-pathway marker relevant to mood and aging.

A marker of adrenaline/noradrenaline turnover.

Functional B12 status at the cellular level.

Reflects glutathione demand and turnover.

Byproducts of gut-bacteria imbalance.

Fatty-acid oxidation markers pointing to carnitine or B2 needs.

A key energy-cycle metabolite and longevity molecule.

Reveal shifts away from efficient aerobic energy.

A neurotoxic tryptophan metabolite tied to brain inflammation.

A dopamine breakdown product reflecting that neurotransmitter's status.

A serotonin breakdown product.

A functional folate-status marker.

Urinary signs of yeast overgrowth.

High levels burden kidneys and tissues.

Measures the rate your bone is being broken down.

A protein reflecting bone formation and metabolism.

Directs calcium into bone and away from arteries.

Reflects muscle turnover and damage.

A simple, powerful predictor of muscle aging and mortality.

Measures the rate of new bone building.

A bone-building enzyme distinct from liver ALP.

Governs calcium balance between blood and bone.

A muscle protein released with tissue breakdown.

Track breakdown of the body's structural scaffolding.

Your biological age estimated from DNA methylation patterns.

Separate biological ages for heart, brain, kidney, and more.

Epigenetic estimate of immune-system age and reserve.

Predicts cardiorespiratory fitness from DNA marks.

A multi-omic epigenetic clock integrating proteins and metabolites into biological age.

How fast you are aging right now, in biological years per calendar year.

The protective caps on chromosomes that shorten as cells age.

A methylation-based read of long-term inflammatory aging.

Epigenetic signatures of metabolic health trajectory.

Red-cell omega-3 level; a strong predictor of cardiovascular longevity.

A structural omega-3 essential for brain and retina.

Combined level of protective omega-3 fats.

An omega-6 precursor to inflammatory signals.

A precise gauge of your inflammatory-fat balance.

An anti-inflammatory marine omega-3.

An intermediate omega-3 with its own benefits.

Combined omega-6 fats; excess skews toward inflammation.

The most common dietary omega-6 fat.

The overall dietary-fat balance driving inflammatory tone.

The protective estrogen-clearance pathway.

A proliferative estrogen metabolite.

A fully detoxified, safe estrogen end-product.

Secondary estrogen within the clearance map.

A downstream androgen metabolite.

Reflect potent-androgen activity in tissues.

Adrenal-androgen output and reserve.

A cortisone metabolite complementing the cortisol picture.

The inactive cortisol counterpart in the stress map.

A progesterone metabolite reflecting its production.

An adrenaline-pathway metabolite for stress mapping.

A more DNA-damaging estrogen metabolite to keep low.

The classic estrogen-safety ratio.

Active estrogen measured in the metabolite context.

The gentlest estrogen in the metabolite panel.

An androgen breakdown product showing metabolism direction.

Androgen output within the metabolic pathway.

A cortisol metabolite showing total cortisol production.

Your true daily cortisol output, beyond single snapshots.

The measurable read of overnight melatonin production.

A dopamine-pathway marker within the hormone panel.

Oxidative DNA-damage marker bundled with hormones.

Keystone beneficial microbes that decline with age.

A major butyrate producer tied to gut and metabolic health.

Core commensals central to microbiome balance.

Normal-flora E. coli levels within the ecosystem.

Opportunists linked to autoimmune flare risk.

Commensals that can turn opportunistic.

Sulfate-reducing microbes tied to gut inflammation.

A common parasite of debated significance.

Protective bacteria supporting barrier and immune balance.

Beneficial fiber-fermenting, butyrate-making bacteria.

Fiber-associated bacteria shaping the gut signature.

A pathogenic overgrowth risk after antibiotics.

Opportunistic bacteria associated with inflammation.

A methane-producer linked to constipation-type symptoms.

The most common yeast overgrowth species.

A waterborne parasite causing malabsorption.

Distinct liver-toxic, carcinogenic mold toxins.

A mold toxin related to aflatoxin.

An emerging mold toxin affecting mitochondria.

A toxin from water-damaged-building mold.

Cumulative lead burden released from stores.

Distinguishes toxic from harmless dietary arsenic.

A metal linked to allergy and oxidative stress.

Environmental metal burden marker.

An environmental element affecting potassium handling.

Kidney- and neuro-toxic mold compound.

Highly potent immune-toxic mold metabolites.

A kidney-toxic mold compound.

Tissue mercury burden assessed after chelation challenge.

A smoking- and food-derived kidney toxin.

A rare but potent neurotoxic metal.

An industrial toxic-metal exposure marker.

A nephrotoxic heavy element tracked in urine.

An industrial-exposure metal marker.

Central to Alzheimer's-type plaque biology.

Linked to Parkinson's-type neurodegeneration.

Targets the myelin sheath in demyelinating conditions.

Involved in nerve-conduction autoimmune disease.

Cause autoimmune encephalitis with psychiatric features.

Associated with autoimmune neurological excitability.

Involved in neuromuscular autoimmune conditions.

Target cerebellar coordination cells.

Target the internal scaffolding of neurons.

Reflects neurofibrillary tangle formation.

A blood-brain-barrier integrity marker.

A core myelin autoimmune target.

Target nerve-cell adhesion structures.

Linked to autoimmune memory and seizure disorders.

Bridges neurological and metabolic autoimmunity.

Linked to nerve-excitability autoimmune syndromes.

A marker of astrocyte injury and neuroinflammation.

Associated with peripheral neuropathy.

Directly measured peak oxygen uptake; a top lifespan predictor.

The ceiling of sustainable hard effort.

How well you switch between burning fat and carbs.

How much energy you draw from fat at rest and low effort.

Pattern and quality of respiration under stress.

The intensity where fat-burning gives way to sugar-burning.

How economically your lungs move air during exertion.

Measured resting calorie burn for precise nutrition.

How much blood your heart moves under load.

A 14-marker bundle covering glucose, kidney, liver, and electrolytes.

A pancreatic digestive enzyme.

The definitive marker of heart-muscle injury.

A methylation-dependent vascular and cognitive risk marker.

Blood sugar handling after a measured load.

Refines prostate risk interpretation.

Bile and oxidative-stress-sensitive liver enzyme.

The more specific pancreatic enzyme.

A cardiac-specific muscle-damage marker.

Insulin response after glucose, revealing hidden resistance.

A prostate-health and screening marker for men.

Essential for converting food into cellular energy.

Precursor to NAD+, a central longevity molecule.

A cofactor for neurotransmitters and methylation.

Central to DNA synthesis and repair.

The clotting-related form of vitamin K.

Vital for cell membranes, brain, and liver fat handling.

Shuttles fat into mitochondria for energy.

Supports insulin action and blood-sugar control.

Needed for sulfite and toxin-clearing enzymes.

Powers energy production and glutathione recycling.

Needed to make coenzyme A for energy metabolism.

Supports metabolism, hair, skin, and nails.

The core energy-and-repair coenzyme that declines with age.

A versatile antioxidant that regenerates others.

Supports insulin signaling and mood regulation.

The essential building block of thyroid hormone.

A cofactor for antioxidant and bone enzymes.

Supports bone and hormone metabolism.

A building block of collagen, glutathione, and calm.

The gut's main fuel and an immune-support amino acid.

Supports heart, bile, and antioxidant defense; declines with age.

The methylation-cycle starting amino acid.

Boosts nitric oxide and marks gut-lining health.

A branched-chain amino acid for muscle and energy.

Essential for collagen and immune function.

The precursor to dopamine and thyroid hormone.

A precursor to histamine and a tissue antioxidant.

Amino acids feeding the energy and urea cycles.

Supports methylation and brain-cell membranes.

Supports methylation and brain-cell membranes.

The rate-limiting amino acid for glutathione.

The precursor to blood-vessel-relaxing nitric oxide.

The key muscle-protein-building amino acid.

The third branched-chain muscle amino acid.

The precursor to serotonin and melatonin.

An essential amino acid feeding dopamine pathways.

Supports gut mucus and connective tissue.

A urea-cycle amino acid for ammonia clearance.

A broad tumor marker used in monitoring.

An ovarian-cancer surveillance marker.

A liver and germ-cell tumor marker.

Prostate surveillance marker for men.

Emerging blood test detecting cancer signals early.

Associated with pancreatic and GI cancers.

Used in breast-cancer monitoring.

A germ-cell and pregnancy-related marker.

Reflects cell-proliferation rate.

A screen for shared cancer signals across many types.

A driver of the inflammatory cascade.

A key anti-inflammatory, balancing cytokine.

A major immune-activating signal.

A rising star among aging and mortality biomarkers.

Total complement activity of the immune system.

A classic, nonspecific inflammation marker.

A sensitive acute-phase inflammatory protein.

Recruits inflammatory cells to tissue.

Central to autoimmune-type inflammation.

Soluble TNF receptors tracking chronic inflammation.

A general marker of chronic immune activation and organ risk.

Core complement proteins in inflammation and autoimmunity.

When high without iron overload, flags inflammation.

Reflects allergic-type inflammatory activity.

The core read of your methylation capacity.

A key conjugation molecule for toxin clearance.

Enzyme activity central to phase-II detox.

A neurotoxic byproduct the liver must clear.

Signals glutathione depletion under toxic load.

Styrene-exposure detox markers.

Intermediates showing where methylation stalls.

Reflect a major liver detox pathway.

Supports ammonia clearance and energy.

A urea-cycle marker for ammonia handling.

A solvent-exposure detox marker.

Reflect conjugation of environmental toxins.

Reflect dopamine — motivation, focus, and reward.

Reflect serotonin — mood, sleep, and calm.

Balances neurotoxic vs neuroprotective pathways.

Reflects a neuroprotective tryptophan branch.

The excitation-inhibition balance of the brain.

Track the alertness-and-stress neurotransmitter.

A tryptophan-pathway branch tied to inflammation.

A functional marker of vitamin B6 status.

Reflect the brain's main calming neurotransmitter.

Availability of the serotonin/melatonin precursor.

Sugar-damaged proteins that stiffen tissues and drive aging.

A reactive sugar byproduct that damages proteins and DNA.

Reflect the nutrient-sensing switch between growth and repair.

Reflect NAD+-dependent longevity enzymes.

A classic marker of cellular senescence burden.

A non-invasive read of accumulated tissue glycation.

A longevity protein whose decline accelerates aging.

Track the energy-sensor that promotes cellular cleanup.

Signals from 'zombie' cells that inflame neighboring tissue.

A double-edged marker of oxidative balance and metabolic risk.

The onset and level of your sleep-signaling hormone.

How cortisol should decline across the day for good sleep.

A physiological readout of circadian alignment.

A simple, powerful marker of cardiovascular fitness.

The nighttime repair hormone tied to deep sleep.

The healthy morning cortisol surge that primes your day.

Balances stress load against adrenal reserve.

A window into autonomic recovery and stress resilience.

Objective sleep duration, efficiency, and timing.

The hunger-hormone balance that circadian disruption distorts.

The core balance of helper to killer T-cells; inverts with immune aging.

T-cells committed to past exposures; they accumulate as naive cells fade.

Worn-out T-cells that crowd the immune system and drive inflammaging.

The immune system's brakes; imbalance drives autoimmunity or poor defense.

Brand-new T-cells just released by the thymus.

A composite methylation-based estimate of biological immune age.

Fresh, unassigned T-cells ready for new threats; they dwindle with age.

A leading candidate marker of true immune age.

T-cells shut down by chronic stimulation; a marker of immune fatigue.

A direct measure of fresh thymic output and immune-regeneration capacity.

The breadth of your immune repertoire; narrows with age.

A cytokine-derived score predicting immune-driven aging and frailty.

Signals active clot formation and breakdown; a thrombotic-tone screen.

High levels independently raise clotting and thrombosis risk.

The enzyme that keeps vWF in check; low levels drive microclotting.

A genetic particle that is both atherogenic and pro-clotting.

A natural anticoagulant; deficiency raises clot risk.

Works with Protein C to prevent excess clotting.

An inherited variant increasing clot tendency.

Antiphospholipid antibodies driving autoimmune clotting.

Total complement activity; low values flag consumption in clotting/autoimmune illness.

A clotting protein that also tracks inflammation and clot burden.

A clotting protein released by stressed, aging endothelium.

Shuts down clot dissolution; links clotting to metabolic and endothelial aging.

Elevates clotting risk and injures the vessel lining.

A natural clot-controlling protein.

The most common inherited clotting mutation.

An antiphospholipid marker raising clot and pregnancy-loss risk.

Confirms antiphospholipid syndrome risk.

A provoked assessment of overall clotting tendency.

An innate-immune activation marker often elevated in mold and biotoxin illness.

A fibrosis-and-inflammation cytokine; orderable at Quest and LabCorp.

Often low in CIRS, linking poor oxygen delivery to fatigue and exercise intolerance.

A regulatory hormone low in the CIRS model, tied to mucosal immunity and sleep.

Paired to assess the neuroendocrine dysregulation described in CIRS.

Urinary mold-toxin burden central to biotoxin-illness workups.

A complement fragment reflecting acute innate immune activation.

Reflects leukocyte migration and blood-brain-barrier permeability under inflammation.

A master regulatory hormone frequently depleted in chronic biotoxin illness.

The specific MSH fragment referenced in biotoxin-illness research.

A deep-nasal-swab culture for biofilm-forming staph; reserved for suspected CIRS.

The Shoemaker-model susceptibility typing; HLA typing is real, its CIRS reading is specialized.

The major genetic influence on Alzheimer's risk and lipid handling.

The most common inherited clotting mutation.

Affects methylation and homocysteine; popular but often over-interpreted.

Predicts how you metabolize many medications.

Antigen-presentation typing relevant to autoimmune and biotoxin susceptibility.

A second glutathione-transferase deletion lowering detox capacity.

The master switch of antioxidant defense; weak variants raise oxidative load.

Encodes mitochondrial superoxide dismutase; variants weaken defense.

Protects tissue against oxidative injury.

Governs breakdown of hydrogen peroxide.

Recognizes gram-positive bacteria, fungi, and Borrelia.

Controls gut microbiome makeup, B12 status, and infection susceptibility.

Influences baseline inflammatory tone.

Supports methylation cycle recycling of B12.

Governs breakdown of catecholamines and estrogen.

Influences neuroplasticity and brain resilience.

A key regulator of LDL clearance and a major drug target.

Detects inherited iron overload that drives oxidative organ damage.

An inherited variant raising clot risk.

Genetic gatekeeper for celiac disease risk.

Inherited risk for lung and liver disease.

Absence sharply reduces glutathione-based toxin clearance.

Shapes glutathione-transferase activity and xenobiotic handling.

Regulates NRF2 and the antioxidant response.

Glutathione-peroxidase gene central to antioxidant capacity.

An antioxidant and detox enzyme gene.

Senses bacterial toxins and fungi; variants alter innate response.

An immune-regulation and gut-inflammation gene.

Variants predispose to higher inflammatory responses.

Shapes anti-inflammatory balance.

A methylation-pathway gene affecting sulfur and homocysteine handling.

Affects choline demand and membrane/liver health.

Sets genetically determined Lp(a) and cardiovascular risk.

Shapes how efficiently you convert dietary omega-3/6 fats.